Conserved Site

Interleukin-7/Interleukin-9, conserved site (IPR018049)

Short name: IL-7/IL-9_CS

Description

Interleukin-7 (IL-7) [PMID: 2663018] is a cytokine that serves as a growth factor for early lymphoid cells of both B- and T-cell lineages. Interleukin-9 (IL-9) [PMID: 1971295] is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T-cells.

Interleukin-7 and -9 seems to be evolutionary related [PMID: 15335670]. This entry represents a conserved region located in the C-terminal section of the proteins.

GO terms

Biological Process

GO:0006955 immune response

Molecular Function

GO:0005126 cytokine receptor binding
GO:0008083 growth factor activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns