Sulphate anion transporter, conserved site (IPR018045)
Short name: S04_transporter_CS
A number of proteins involved in the transport of sulphate across a membrane as well as some yet uncharacterised proteins have been shown [PMID: 8140616, PMID: 7616962] to be evolutionary related. These proteins are:
- Neurospora crassa sulphate permease II (gene cys-14).
- Yeast sulphate permeases (genes SUL1 and SUL2).
- Rat sulphate anion transporter 1 (SAT-1).
- Mammalian DTDST, a probable sulphate transporter which, in human, is involved in the genetic disease, diastrophic dysplasia (DTD).
- Sulphate transporters 1, 2 and 3 from the legume Stylosanthes hamata.
- Human pendrin (gene PDS), which is involved in a number of hearing loss genetic diseases.
- Human protein DRA (Down-Regulated in Adenoma).
- Soybean early nodulin 70.
- Escherichia coli hypothetical protein ychM.
- Caenorhabditis elegans hypothetical protein F41D9.5.
These proteins are highly hydrophobic and seem to contain about 12 transmembrane domains.
- PS01130 (SLC26A)