Asn/Gln amidotransferase (IPR018027)

Short name: Asn/Gln_amidotransferase

Overlapping homologous superfamilies


Domain relationships



The GatB domain, the function of which is uncertain, is associated with aspartyl/glutamyl amidotransferase subunit B and glutamyl amidotransferase subunit E. These are involved in the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.