Penicillin-binding protein 2 (IPR017790)

Short name: Penicillin-binding_protein_2

Overlapping homologous superfamilies

Family relationships



This entry represents penicillin-binding protein 2 (PBP-2, also known as peptidoglycan D,D-transpeptidase MrdA), a protein whose gene (designated either pbpA or mrdA) is generally found next to the gene for RodA, a protein required for the rod (bacillus) shape in many bacteria [PMID: 2644207]. PBP-2 acts as a transpeptidase for cell elongation, hence it is involved in formation of the rod shape.

GO terms

Biological Process

GO:0009252 peptidoglycan biosynthetic process

Molecular Function

GO:0008658 penicillin binding
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.