DnaA regulatory inactivator Hda (IPR017788)

Short name: Hda

Overlapping homologous superfamilies

Family relationships


This entry represents the Hda (Homologous to DnaA) proteins, which are about half the length of DnaA and homologous over the entire length of Hda. In Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP, thus inhibiting the inititation of DNA replication [PMID: 16882985].

GO terms

Biological Process

GO:0032297 negative regulation of DNA-dependent DNA replication initiation

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.