Glycoside hydrolase, family 1, beta-glucosidase (IPR017736)

Short name: Glyco_hydro_1_beta-glucosidase

Overlapping homologous superfamilies

Family relationships


O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

Glycoside hydrolase family 1 GH1 comprises enzymes with a number of known activities; beta-glucosidase (EC:; beta-galactosidase (EC:; 6-phospho-beta-galactosidase (EC:; 6-phospho-beta-glucosidase (EC:; lactase-phlorizin hydrolase (EC:, (EC:; beta-mannosidase (EC:; myrosinase (EC:

This enzyme represents beta-glucosidase, which catalyses the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose [PMID: 9466926, PMID: 10960102]. It has a wide substrate specificity for beta-D-glucosides.

GO terms

Biological Process

GO:0030245 cellulose catabolic process

Molecular Function

GO:0008422 beta-glucosidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.