Family

Succinylglutamate-semialdehyde dehydrogenase (IPR017649)

Short name: SuccinylGlu_semiald_DH_AstD

Family relationships

None.

Description

Succinylglutamic-semialdehyde dehydrogenase (or succinylglutamic semialdehyde dehydrogenase (SGSD, E. coli AstD, EC=1.2.1.71)) is the fourth enzyme in the arginine succinyltransferase (AST) pathway for arginine catabolism [PMID: 3144259], and catalyzes the NAD+-dependent reduction of succinylglutamate semialdehyde into succinylglutamate [PMID: 10200310]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.

GO terms

Biological Process

GO:0006527 arginine catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0043824 succinylglutamate-semialdehyde dehydrogenase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
PANTHER
HAMAP
TIGRFAMs