Formylmethanofuran dehydrogenase subunit C (IPR017550)

Short name: Formylmethanofuran_DH_suC

Overlapping homologous superfamilies

Domain relationships


This entry represents the C subunit of formylmethanofuran dehydrogenase (EC:, which is involved in methane biosynthesis from carbon dioxide [PMID: 12102556, PMID: 11532013]. This oxygen-labile enzyme catalyses the reversible oxidation of carbon dioxide and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). There is a tungsten-containing (Fwd) form of this enzyme and a molybdenum-containing (Fmd) form; this entry includes both forms [PMID: 11913137]. Formylmethanofuran dehydrogenase is composed of 5-7 subunits, of which subunit C (FwdC or FmdC) is one. The enzymes in this entry are largely from archaeal species. Nomenclature in some bacteria may reflect inclusion of the formyltransferase described by IPR014053 as part of the complex.

GO terms

Biological Process

GO:0015948 methanogenesis
GO:0055114 oxidation-reduction process

Molecular Function

GO:0018493 formylmethanofuran dehydrogenase activity
GO:0046914 transition metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.