Family

Protein lin-7 (IPR017365)

Short name: LIN7

Overlapping homologous superfamilies

Family relationships

None.

Description

There are three mammalian LIN7 homologues, LIN7A/B/C [PMID: 17237226]. LIN7 contains single L27 and PDZ domains.

Protein lin-7 plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells [PMID: 12967566]. The three components LIN7A, B and C form a complex with CASK and APBA1 which is thought to have roles in neurone synapses [PMID: 15317815].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF