Family

Methyl-CpG-binding domain protein 4 (IPR017352)

Short name: MBD4

Family relationships

None.

Description

Methyl-CpG-binding domain protein 4 (MBD4) is a mismatch-specific DNA N-glycosylase involved in DNA repair. It has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites [PMID: 9774669, PMID: 10930409].

GO terms

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003677 DNA binding
GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
PIRSF