Family

UBX domain-containing protein 2/7 (IPR017346)

Short name: UBX_7/2

Overlapping homologous superfamilies

Family relationships

None.

Description

This entry represents UBX domain-containing proteins 2 (Ubx2) and 7 (UBXN7).

VCP/p97 or Cdc48 is a eukaryotic ATPase involved in membrane fusion, protein transport, and protein degradation. Ubx2 interacts with Cdc48 in fission yeast [PMID: 15120077]. UBXN7 is a ubiquitin-binding adapter that links a subset of NEDD8-associated cullin ring ligases (CRLs) to VCP/p97 to regulate turnover of their ubiquitination substrates [PMID: 22537386].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF