Family

U1 small nuclear ribonucleoprotein C (IPR017340)

Short name: U1_snRNP-C

Family relationships

None.

Description

This group represents U1 small nuclear ribonucleoprotein C. It is a component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA [PMID: 2136774, PMID: 1826349, PMID: 8798632].

GO terms

Biological Process

GO:0000398 mRNA splicing, via spliceosome
GO:0000387 spliceosomal snRNP assembly

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005685 U1 snRNP

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
HAMAP
PIRSF