Peptidoglycan recognition protein, PGRP-S (IPR017331)

Short name: Peptidoglycan_recognition

Overlapping homologous superfamilies

Family relationships


PGRP-S (peptidoglycan recognition protein short, also known as peptidoglycan recognition protein 1) is a innate immunity pattern recognition protein conserved from insects to mammals, recognising bacterial cell wall peptidoglycan and activates two antimicrobial defense systems, prophenoloxidase cascade and antimicrobial peptides through Toll receptor [PMID: 12649138].

Peptidoglycan recognition proteins (PGRPs) are part of the host's innate immune system. In mammals, only four types of PGRPs, long PGRPs, intermediate PGRPs and short PGRPs have so far been identified [PMID: 23149273].

GO terms

Biological Process

GO:0045087 innate immune response

Molecular Function

GO:0042834 peptidoglycan binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.