Peptidase S1A, HAT/DESC1 (IPR017329)

Short name: Pept_S1A_HAT/DESC1

Overlapping homologous superfamilies

Family relationships


This entry represents the type II transmembrane serine proteases (TTSPs), which belong to MEROPS peptidase family S1A (clan PA(S)). They include the HAT/DEASC1-like (human airway trypsin-like protease/ differentially expressed in squamous cell carcinoma gene 1) serine peptidases. They are activated by cleavage and secreted [PMID: 17388811]. The entry includes the adrenal secretory serine peptidases, which are HAT peptidases that play an important role in airway physiology [PMID: 20620066].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004252 serine-type endopeptidase activity

Cellular Component

GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.