Family

Peptidase S8A, subtilisin-like peptidase 1, plasmodium (IPR017314)

Short name: Pept_S8A_PfSUB_1

Family relationships

Description

This entry contains serine peptidases belonging to MEROPS peptidase family S8A (subtilisin family, clan SB). All of the peptidases in this entry derive from Plasmodium spp. and are called 'subtilisin-like peptidase 1'.

The peptidase in Plasmodium falciparum (isolate 3D7) termed pfSUB1 is a component of the exoneme [PMID: 18083092]. PfSUB1 mediates the proteolytic maturation of at least two essential members of another enzyme family called SERA. This proteolytic processing event is required for the release of viable parasites from the host erythrocyte [PMID: 18083098].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF