Family

Cyclin-dependent kinase 2-associated protein 1/2 (IPR017266)

Short name: DOC_1/2

Family relationships

None.

Description

This group represents the cyclin-dependent kinase 2-associated protein 1/2 (DOC-1/1R). DOC-1 is a specific inhibitor of the cell-cycle kinase CDK2 [PMID: 10938106]. DOC-1R associates with CDK2 and inhibits CDK2 activation by obstructing its association with cyclin E and A [PMID: 23781148].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF
PANTHER