Family

Bone morphogenetic protein 3/3B (IPR017197)

Short name: BMP3/BMP3B

Overlapping homologous superfamilies

None.

Family relationships

Description

This group includes two members of the TGF-beta superfamily: bone morphogenetic protein 3 (BMP3) and bone morphogenetic protein 3B (BMP3B), also known as growth differentiation factor 10 (GDF10). Together they represent a subgroup of the BMP family. They are involved in development and organogenesis. In developing embryos, they have different dorsalising activities [PMID: 14977563]. BMP3 is a negative regulator of bone density [PMID: 11138004]. BMP3B plays an inhibitory role in the process of osteoblast differentiation [PMID: 22155034].

GO terms

Biological Process

GO:0001649 osteoblast differentiation

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF