Serine/threonine-protein kinase Unc-51 (IPR017184)

Short name: Ser/Thr_kinase_Unc51

Overlapping homologous superfamilies


Family relationships



This entry represents serine/threonine-protein kinases (EC: such as Unc-51 from Caenorhabditis elegans. Unc-51 is important for axonal elongation and axonal guidance [PMID: 16887826]. It is required for either the maintenance of axons (membrane turnover) or for an unknown neuronal function. C elegans worms lacking Unc-51 exhibit various abnormalities in axonal elongation and axonal structures. Unc-51 could also help control cell size along with Bec-1, as mutations in their corresponding genes results in a reduction in small body size without affecting cell number [PMID: 17890369].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004672 protein kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.