Family

Gremlin-1/2 (IPR017159)

Short name: Gremlin-1/2

Family relationships

None.

Description

This entry includes Gremlin-1 and -2. Gremlin 1 (grem 1) is known for its antagonistic reaction with bone morphogenetic proteins (BMPs) in the TGF beta signalling pathway. Grem 1 acts as a cytokine that regulates embryonic morphogenesis via BMP family members [PMID: 15201225, PMID: 17522159].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF