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Overview
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Pathways & interactions
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Structures
Arylacetamide deacetylase (IPR017157)
Short name: Arylacetamide_deacetylase
Overlapping homologous superfamilies
- Alpha/Beta hydrolase fold (IPR029058)
Family relationships
None.
Description
The lipase arylacetamide deacetylase is involved in the utilisation of triacylglycerol (TAG) for the assembly of very-low-density lipoprotein (VLDL) in the secretory apparatus of the hepatocyte, as the process is mobilized by lipolysis of the cytosolic TAG pool, followed by re-esterification [PMID: 14748713]. The enzyme competes with cytosolic arylamine N-acetyltransferase, which catalyses one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens in many tissues in many species [PMID: 8063807].
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0052689 carboxylic ester hydrolase activity
Cellular Component
GO:0016021 integral component of membrane
Contributing signatures
- PIRSF037251 (Arylacetamide_deacetylase)