Family

Adaptor protein complex AP-4, epsilon subunit (IPR017109)

Short name: AP4_complex_esu

Family relationships

None.

Description

Adapter-like complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1 and beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1). It is a subunit of a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system [PMID: 11409905, PMID: 20972249].

This group represents an adaptor protein complex AP-4, epsilon subunit.

GO terms

Biological Process

GO:0015031 protein transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0030124 AP-4 adaptor complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF