Acid sphingomyelinase-like phosphodiesterase, predicted (IPR017064)

Short name: ASM-like_Pdiesterase_prd

Overlapping homologous superfamilies

Family relationships



This group represents a predicted acid sphingomyelinase-like phosphodiesterase (ASMLPD). The ASMLPD 3b precursor has a possible interaction with the anti-CD20 monoclonal antibodies called rituximab [PMID: 16223774]. This indicates that it may have a role in immune responses.

GO terms

Biological Process

GO:0006685 sphingomyelin catabolic process

Molecular Function

GO:0004767 sphingomyelin phosphodiesterase activity

Cellular Component

GO:0005615 extracellular space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.