mRNA cap guanine-N7 methyltransferase, eukaryotes (IPR016899)

Short name: mRNA_G-N7_MeTrfase_euk

Overlapping homologous superfamilies

Family relationships


mRNA (guanine-N(7))-methyltransferase methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. It binds RNA containing 5'-terminal GpppC [PMID: 10679253, PMID: 7623811, PMID: 9790902, PMID: 9705270, PMID: 10347220, PMID: 22099306]. This family of enzymes is found in nucleus [PMID: 11018011, PMID: 11114884, PMID: 15767670].

GO terms

Biological Process

GO:0006370 7-methylguanosine mRNA capping

Molecular Function

GO:0004482 mRNA (guanine-N7-)-methyltransferase activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.