Family

COP9 signalosome complex, subunit 9 (IPR016806)

Short name: COP9_signalosome_su9

Family relationships

None.

Description

CNS9 is a component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes [PMID: 12186635, PMID: 12672462]. The CSN complex is involved in the regulation of the mating pheromone response [PMID: 12446563].

The COP9 signalosome-like (CSN) complex is composed of at least 6 members:

  • RRI1/CSN5,
  • CSN9,
  • RRI2/CSN10,
  • PCI8/CSN11,
  • CSN12,
  • CSI1.

In the complex CNS9 probably interacts directly with CSN12 and CSI1 and also RPN5.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0008180 COP9 signalosome

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
PIRSF