Pathways & interactions
COP9 signalosome complex subunit 9 (IPR016806)
Short name: Csn9
Overlapping homologous superfamilies
Csn9 is a component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes [PMID: 12186635, PMID: 12672462]. The CSN complex is involved in the regulation of the mating pheromone response [PMID: 12446563].
The COP9 signalosome-like (CSN) complex in yeast is composed of at least 6 members:
In the complex Csn9 probably interacts directly with Csn12 and Csi1 and also Rpn5.
- PIRSF022632 (UCP022632)