Family

Interferon alpha/beta receptor 1 (IPR016669)

Short name: Interferon_alpha/beta_rcpt-1

Family relationships

None.

Description

The interferon-alpha/beta receptor 1 family of proteins associates with IFNAR2 to form the type I interferon receptor. Binding of interferons alpha and beta to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.

GO terms

Biological Process

GO:0019221 cytokine-mediated signaling pathway

Molecular Function

GO:0004904 interferon receptor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF