Prefoldin, subunit 4 (IPR016661)

Short name: PFDN4

Overlapping homologous superfamilies

Family relationships


This group represents a prefoldin, subunit 4 (PFDN4, also known as Gim3 in budding yeasts). PFDN4 is part of the prefoldin heterohexamer copmlex (consists of two PFD-alpha type and four PFD-beta type subunits) that binds specifically to cytosolic chaperonin (c-CPN) and transfers targeted proteins to it. It binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins [PMID: 9630229, PMID: 17936702].

GO terms

Biological Process

GO:0006457 protein folding

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016272 prefoldin complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.