Family

tRNA (guanine(9)-N(1))-methyltransferase TRM10/TRM10A (IPR016653)

Short name: TRM10/TRM10A

Overlapping homologous superfamilies

Family relationships

Description

Yeast tRNA (guanine(9)-N1)-methyltransferase TRM10 catalyses the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNAs [PMID: 12702816, PMID: 15640439]. This group also includes metazoa homologue A (TRM10A). In humans there are three TRM10 orthologues; a nonsense mutation in TRMT10A has been associated with microcephaly [PMID: 25053765].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
PIRSF