Family

Nicalin (IPR016574)

Short name: Nicalin

Family relationships

None.

Description

Nicalin is a Nodal signalling antagonist and a distant homologue of the gamma-secretase component Nicastrin [PMID: 15257293]. In humans, Nicalin forms a complex with NOMO (Nodal modulator) and controls the assembly and stability of this complex [PMID: 17261586].

GO terms

Biological Process

GO:0009966 regulation of signal transduction

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF