Family

Cyclic 2, 3-diphospoglycerate synthetase (IPR016557)

Short name: Cyc_diphosphoglycerate_synth

Family relationships

None.

Description

Cyclic 2,3-diphospoglycerate (cDPG) is a low molecular weight compound that accumulates to high levels in some hyperthermophilic methanogens, suggesting that it may play a thermoadaptive role. In support of this, cDPG has been shown to protect proteins from heat denaturation in vitro. This entry represents cDPG synthetase, which catalyzes the synthesis of cDPG by the formation of an intramolecular phosphoanhydride bond in 2,3-diphosphoglycerate [PMID: 9811660].

GO terms

Biological Process

GO:0006094 gluconeogenesis

Molecular Function

GO:0036356 cyclic 2,3-diphosphoglycerate synthetase activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP
PIRSF