Epoxide hydrolase (IPR016292)

Short name: Epoxide_hydrolase

Overlapping homologous superfamilies

Family relationships


This entry includes epoxide hydrolase 1 (EPHX1) from mammals and juvenile hormone epoxide hydrolase (JHEH) from insects. EPHX1 is a conserved biotransformation enzyme for converting epoxides to diols and has been linked to several human diseases including cancer [PMID: 26216302]. JHEH catalyzes juvenile hormone hydrolysis [PMID: 15681225].

This entry also includes uncharacterised proteins from bacteria and archaea.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0033961 cis-stilbene-oxide hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.