Lipase, LIPH-type (IPR016272)

Short name: Lipase_LIPH

Overlapping homologous superfamilies

Family relationships


This group represents LIPH (lipase H)-type lipases [PMID: 12213196]. It includes lipase H, lipoprotein lipase (LPL), and hepatic and pancreatic lipases.

LIPH hydrolyses specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid [PMID: 12063250, PMID: 12963729].

GO terms

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0052689 carboxylic ester hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.