UTP--glucose-1-phosphate uridylyltransferase (IPR016267)

Short name: UDPGP_trans

Overlapping homologous superfamilies

Family relationships

  • UDPGP family (IPR002618)
    • UTP--glucose-1-phosphate uridylyltransferase (IPR016267)


UDP-glucose is the universal activated form of glucose, employed in all organisms for glucosyl transfer reactions and as precursor for various activated carbohydrates [PMID: 17010990]. It is formed by the enzyme UDP-glucose pyrophosphorylase (UGPase, UDPGP), also known as UTP--glucose-1-phosphate uridylyltransferase, (EC:, which catalyses the reaction UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose. The enzymatically active form of the protein is a homooctamer in Saccharomyces cerevisiae [PMID: 17010990].

GO terms

Biological Process

GO:0006011 UDP-glucose metabolic process

Molecular Function

GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.