Pathways & interactions
Serine/threonine-protein kinase Mps1 (IPR016242)
Short name: Mps1
Overlapping homologous superfamilies
- Protein kinase Mps1 family (IPR027084)
- Serine/threonine-protein kinase Mps1 (IPR016242)
Mps1 is a serine/threonine-protein kinase involved in the phosphorylation of many mitotic regulators. It is required for spindle pole body (SPB) duplication and spindle checkpoint function [PMID: 7737118, PMID: 8567717]. It is involved in sister chromatid biorientation in mitosis and meiosis [PMID: 23371552]. The expression of Mps1 is regulated in a cell cycle-dependent manner, and the activity of Mps1 can be regulated through autophosphorylation [PMID: 17728254].
No terms assigned in this category.
- PIRSF000611 (Ser/Thr_PK_MPS1)