Homologous Superfamily

D-lactate dehydrogenase, C-terminal subdomain 1 (IPR016172)

Short name: D-lactate_DH_C-sub1

Overlapping entries


The C-terminal domain of certain FAD-linked oxidases consist of two structural subdomains: subdomain 1 is a 2-layer a/b or 3-layer a/b/a sandwich, and subdomain 2 is either an orthogonal alpha-bundle or a second 2-layer a/b sandwich. This entry represents the first (N-terminal) subdomain with a 2-layer alpha/beta sandwich fold. This subdomain is found in D-lactate dehydrogenases (EC:, EC: -cytochrome), a peripheral membrane respiratory enzyme involved in electron transfer for the energization of active transport of a variety of sugars and amino acids in bacteria [PMID: 10944213]. It is also found in certain cholesterol oxidases (EC:, monomeric flavoenzymes that catalyses the oxidation and isomerisation of cholesterol to cholest-4-en-3-one [PMID: 11397813].

GO terms

Biological Process

GO:0006089 lactate metabolic process
GO:0055085 transmembrane transport

Molecular Function

GO:0050660 flavin adenine dinucleotide binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.