Pili assembly chaperone, N-terminal (IPR016147)

Short name: Pili_assmbl_chaperone_N

Overlapping homologous superfamilies

Domain relationships



Most Gram-negative bacteria possess a supramolecular structure - the pili - on their surface, which mediates attachment to specific receptors. Many interactive subunits are required to assemble pili, but their assembly only takes place after translocation across the cytoplasmic membrane. Periplasmic chaperones assist pili assembly by binding to the subunits, thereby preventing premature aggregation [PMID: 8670884, PMID: 1683764]. Pili chaperones are structurally, and possibly evolutionarily, related to the immunoglobulin superfamily [PMID: 1348692, PMID: 17082819]: they contain two globular domains, with a topology identical to an immunoglobulin fold [PMID: 2478891].

This entry represents the N-terminal domain.

GO terms

Biological Process

GO:0071555 cell wall organization

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0030288 outer membrane-bounded periplasmic space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.