Homologous Superfamily

Ubiquitin-conjugating enzyme/RWD-like (IPR016135)

Short name: UBQ-conjugating_enzyme/RWD

Overlapping entries


This superfamily represents a structural domain with an alpha-beta(4)-alpha(3) core fold. Domains of this structure are found in:

  • Ubiquitin conjugating enzyme E2, as well as related proteins such as ubiquitin carrier protein 4 and ubiquitin-protein ligase W [PMID: 11885984].
  • The UEV domain in tumour susceptibility gene 101 [PMID: 16552148] and vacuolar protein sorting-associated protein [PMID: 15044434].
  • RWD domain, found in RING finger and WD repeat-containing proteins, such as EIF-2 kinase 4 (GCN2-like protein) [PMID: 15273307].
  • UFC1-like domain found in Ufm1-conjugating enzyme 1 [PMID: 17825256].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.