Homologous Superfamily

Bromoperoxidase/chloroperoxidase C-terminal (IPR016119)

Short name: Br/Cl_peroxidase_C

Overlapping entries


This superfamily represents an alpha helical domain is found in bromoperoxidases and at the C-terminal of chloroperoxidases, both being haloperoxidases [PMID: 10843856]. The structure of chloroperoxidase from the fungus Curvularia inaequalis consists of a duplication containing two core alpha-helical bundles arranged as in other family dimers [PMID: 10499093]. Chloroperoxidases (EC: use a haem cofactor to bring about the chlorination of a range of organic molecules, forming stable C-Cl bonds.

The vanadium-dependent haloperoxidases exclusively catalyse the oxidation of halides. Vanadium-dependent haloperoxidase has an almost all-helical structure, with two four-helix bundles and only three small beta-sheets. The holoenzyme contains trigonal-bipyramidal coordinated vanadium atoms at its two active centres.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0004601 peroxidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.