Domain

Histidine decarboxylase proenzyme, subdomain (IPR016106)

Short name: Pyr-dep_his-deCO2ase_subdom

Domain relationships

None.

Description

This entry represents a structural subdomain found in Histidine decarboxylase proenzyme. This subdomain has an irregular structure containing both beta-strand and alpha-helical regions. These proteins form heterohexamers [PMID: 11243783].

Histidine decarboxylase catalyses the formation of histamine from histidine. It requires a pyruvoyl group for its activity. Cleavage of the proenzyme PI chain yields two subunits, alpha and beta, which arrange as a hexamer (alpha beta) 6 by nonhydrolytic self-catalysis.

GO terms

Biological Process

GO:0006547 histidine metabolic process

Molecular Function

GO:0004398 histidine decarboxylase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D