Domain

Superantigen toxin, C-terminal (IPR016091)

Short name: SuperAg_toxin_C

Domain relationships

Description

This entry represents superantigen toxins from Staphylococcus aureus and Streptococcus pyogenes, which share a common core structure consisting of beta(2)-alpha-beta(2). S. aureus toxins with this fold include: enterotoxins A (SEA) [PMID: 7628431], B (SEB) [PMID: 9514739], C2 (SEC2) [PMID: 14559915], C3 (SEC3) [PMID: 11934896] and H (SEH) [PMID: 10986116], heat shock syndrome toxin-1 [PMID: 8759320], and superantigen-like proteins SET1 [PMID: 15213171] and SET3 [PMID: 12082105]. S. pyogenes toxins with this fold include: pyrogenic exotoxins A1 [PMID: 11045630] and Spe-J [PMID: 15247241], and in superantigen proteins Spe-C [PMID: 9253413], Spe-H [PMID: 10860729], Smez-2 [PMID: 10860729] and SSA [PMID: 10048922].

GO terms

Biological Process

GO:0009405 pathogenesis

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY
GENE3D