Chalcone isomerase (IPR016087)

Short name: Chalcone_isomerase

Overlapping homologous superfamilies

Domain relationships



Chalcone isomerase (EC:; also known as chalcone-flavanone isomerase) is a plant enzyme responsible for the isomerisation of chalcone to naringenin, a key step in the biosynthesis of flavonoids. The Petunia hybrida (Petunia) genome contains two genes coding for very similar enzymes, ChiA and ChiB, but only the first seems to encode a functional chalcone isomerase. Chalcone isomerase has a core 2-layer alpha/beta structure consisting of beta(3)-alpha(2)-beta-alpha(2)-beta(3) [PMID: 10966651].

This entry represents chalcone isomerases and enzymes with a common structure.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016872 intramolecular lyase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.