Homologous Superfamily

Acyl transferase/acyl hydrolase/lysophospholipase (IPR016035)

Short name: Acyl_Trfase/lysoPLipase

Overlapping entries

Description

This superfamily represents a structural domain with a 3-layer alpha/beta/alpha topology. This domain can be found in acyl transferases such as bacterial malonyl-CoA ACP transacylase (FabD) and the homologous domain from eukaryotic fatty acid synthase [PMID: 12575934]. This domain is also found in lysophospholipases such as cytosolic phospholipase A2 (which has additional structural features) [PMID: 10319815], and in patatin proteins, which are plant glycoproteins that act as non-specific lipid acyl hydrolases [PMID: 12779324].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY