tRNA methyltransferase TRMD/TRM10-type domain (IPR016009)

Short name: tRNA_MeTrfase_TRMD/TRM10

Overlapping homologous superfamilies

Domain relationships


This domain is found in tRNA methyltransferases including tRNA (guanine-N(1)-)-methyltransferases (TRMD) and mitochondrial ribonuclease P protein 1. Proteins containing this domain also include tRNA (guanine(9)-N1)-methyltransferase (Trm10) from yeasts.

Escherichia coli K12 tRNA (guanine-N(1)-)-methyltransferase catalyses the conversion of a guanosine residue to N1-methylguanine in position 37, next to the anticodon, in tRNA [PMID: 6337136]. Mitochondrial RNase P (mtRNase P) functions in mitochondrial tRNA maturation [PMID: 18984158].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.