Domain

Chemokine-binding M3, subdomain 1, viral (IPR015950)

Short name: Chemokine-bd_M3_sub1_vir

Domain relationships

None.

Description

This entry represents a beta-sandwich domain found in a group of viral chemokine binding proteins. These proteins bind with CC-chemokine MCP-1, acting as cytokine decoy receptors [PMID: 12419245]. For example, the murine herpesvirus decoy receptor M3 acts as an immune system saboteur by altering host anti-viral inflammatory repsonses. M3 adopts a structure consisting of two different beta-sandwich domains of partial topological similarity to immunoglobulin-like folds.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0019956 chemokine binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D