Purple acid phosphatase, N-terminal (IPR015914)

Short name: Purple_acid_Pase_N

Overlapping homologous superfamilies

Domain relationships



Purple acid phosphatases (PAPs) are ubiquitous binuclear metal-containing acid hydrolases characterised by their acidic pH optima and their intense purple colour due to a TyrO-to-FeIII charge-transfer transition. The amino acid residues coordinating the metal ions are conserved in all PAPs. Active PAPs contain an FeIII ion coordinated to Tyr O, a His N, and an Asp O2, in addition to a divalent metal ion (Fe, Zn, or Mn) coordinated by a His N, a His N, and an Asn O. A hydroxide ion and an Asp O2 bridge the two metal ions [PMID: 12440878]. These enzymes share a high degree of homology within their N-termini [PMID: 10510276].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003993 acid phosphatase activity
GO:0046872 metal ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.