Pathways & interactions
Literature: IMP dehydrogenase / GMP reductase, conserved site (IPR015875)
References used in this entry
The following publications were referred to in the abstract:
Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.
Collart FR, Huberman E.
J. Biol. Chem. 263 15769-72 1988
PMID: 2902093 Related citations
Nucleotide sequence of the gene encoding the GMP reductase of Escherichia coli K12.
Andrews SC, Guest JR.
Biochem. J. 255 35-43 1988
PMID: 2904262 Related citations
Two distinct cDNAs for human IMP dehydrogenase.
Natsumeda Y, Ohno S, Kawasaki H, Konno Y, Weber G, Suzuki K.
J. Biol. Chem. 265 5292-5 1990
PMID: 1969416 Related citations
The following publications were not referred to in the abstract, but provide useful additional information:
Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
Gan L, Petsko GA, Hedstrom L.
Biochemistry 41 13309-17 2002
PMID: 12403633 Related citations
Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site.
Prosise GL, Wu JZ, Luecke H.
J. Biol. Chem. 277 50654-9 2002
PMID: 12235158 Related citations
Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
McMillan FM, Cahoon M, White A, Hedstrom L, Petsko GA, Ringe D.
Biochemistry 39 4533-42 2000
PMID: 10758003 Related citations
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Prosise GL, Luecke H.
J. Mol. Biol. 326 517-27 2003
PMID: 12559919 Related citations
The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase.
Gan L, Seyedsayamdost MR, Shuto S, Matsuda A, Petsko GA, Hedstrom L.
Biochemistry 42 857-63 2003
PMID: 12549902 Related citations