Homologous Superfamily

Influenza matrix M1, N-terminal subdomain 2 (IPR015799)

Short name: Flu_matrix_M1_N_sub2

Overlapping entries


Matrix protein (M1) of Influenza virus is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. It is therefore required that M1 binds both membrane and RNA simultaneously [PMID: 9164466]. M1 is comprised of two domains connected by a linker sequence. The N-terminal domain has a multi-helical structure that can be divided into two subdomains: subdomain 1 forms an up-down helical bundle and subdomain 2 forms an orthogonal bundle [PMID: 11162800]. The C-terminal domain also contains alpha-helical structure.

This entry represents the second subdomain of the N-terminal domain of M1.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003723 RNA binding
GO:0005198 structural molecule activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.