Family

Transmembrane emp24 domain-containing protein 7 (IPR015718)

Short name: TMED7

Overlapping homologous superfamilies

Family relationships

  • TMP21-related (IPR015720)
    • Transmembrane emp24 domain-containing protein 7 (IPR015718)

Description

Transmembrane emp24 domain-containing protein 7 (TMED7, also known as p24gamma3 or p27) is related to the p24 family, which is a widely conserved family of transmembrane proteins that plays a functional role in the initiation of assembly of COPI (Coat protein I) coated vesicles. COPI coated vesicles are involved in protein transport within the early secretory pathway [PMID: 15145531, PMID: 9681629].

TMED7 may play a role in vesicular protein trafficking, mainly in the early secretory pathway. It appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications [PMID: 16940185].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER