Domain

GLTSCR protein, conserved region (IPR015671)

Short name: GSCR1_dom

Domain relationships

None.

Description

This domain is found in glioma tumour suppressor candidate region gene 1 (GLTSCR1) protein, and is typically between 105 and 124 amino acids in length. There is a single completely conserved residue F that may be functionally important. Mutations in the gene for this protein in humans leads to the development of oligodendrogliomas [PMID: 15834925]. There is evidence that these protein interacts with SH3 domains [PMID: 17474147].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam