Family

Chromatin modification-related protein Eaf6 (IPR015418)

Short name: Eaf6

Family relationships

None.

Description

Eaf6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 histone acetyltransferase complex is conserved from yeast to humans [PMID: 14966270]. Budding yeast Eaf6 is also a component of the NuA3 histone acetyltransferase complex that acetylates Lys-14 of histone H3 [PMID: 17157260], while human Eaf6 is a component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity [PMID: 18794358].

GO terms

Biological Process

GO:0016573 histone acetylation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0000123 histone acetyltransferase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam