Domain

Activator of Hsp90 ATPase, N-terminal (IPR015310)

Short name: AHSA1_N

Domain relationships

None.

Description

This domain is predominantly found N-terminal in the protein Activator of Hsp90 ATPase (Aha1). Aha1 adopts a secondary structure consisting of an N-terminal alpha-helix leading into a four-stranded meandering antiparallel beta-sheet, followed by a C-terminal alpha-helix. The two alpha helices are packed together, with the beta-sheet curving around them. The N-terminal domain of Aha1 interacts with Hsp90 and stimulates its ATPase activity [PMID: 15039704].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0001671 ATPase activator activity
GO:0051087 chaperone binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY
SMART
Pfam